The journey of Midlands teenager Johanna Morrigan, who reinvents herself as Dolly Wilde: fast-talking, lady sex-adventurer, moves to London, and gets a job as music critic in the hope of saving her poverty stricken family in Wolverhampton. Based on Caitlin Moran's bestselling semi-autobiographical novel.

The concurrent sexual lives of best friends Jonathan and Sandy are presented, those lives which are affected by the sexual mores of the time and their own temperament, especially in relation to the respective women who end up in their lives.

It is 1967, and Larry Gopnik, a physics professor at a quiet Midwestern university, has just been informed by his wife Judith that she is leaving him. She has fallen in love with one of his more pompous acquaintances Sy Ableman.