Dr. Henry Frankenstein attempts to create life by assembling a creature from body parts of the deceased. Aided by his loyal misshapen assistant, Fritz, Frankenstein succeeds in animating his monster, but, confused and traumatized, it escapes into the countryside and begins to wreak havoc. Frankenstein searches for the elusive being, and eventually must confront his tormented creation.

Dr. Henry Jekyll believes that there are two distinct sides to men - a good and an evil side. He believes that by separating the two, man can become liberated. He succeeds in his experiments with chemicals to accomplish this and transforms into Hyde to commit horrendous crimes. When he discontinues use of the drug, it is already too late.