In a futuristic world almost barren of life, mankind is confined to mechanized domed cities where A.I.’s control all aspects of life. In this world, humans are no longer born, they are manufactured in a production line; and alongside them live androids known as autoreivs. Within one of these domed sanctuaries named Romdeau lives Re-l Mayer, one of a few citizens who aren’t entirely prevented from thinking. Her grandfather's prominent position and the affection of the scientist Daedalus have left her more free will than is normally allowed, but Re-l has started to question the sanctity of the city and the citizens' perfect way of life. With mysterious beings known as proxies causing havoc and a man named Vincent causing great influence on her life, Re-l must travel outside of the city to find the answers she seeks and discover the mystery behind "the awakening".

Light Yagami is an ace student with great prospects—and he’s bored out of his mind. But all that changes when he finds the Death Note, a notebook dropped by a rogue Shinigami death god. Any human whose name is written in the notebook dies, and Light has vowed to use the power of the Death Note to rid the world of evil. But will Light succeed in his noble goal, or will the Death Note turn him into the very thing he fights against?

Saitama is a hero who only became a hero for fun. After three years of “special” training, though, he’s become so strong that he’s practically invincible. In fact, he’s too strong — even his mightiest opponents are taken out with a single punch, and it turns out that being devastatingly powerful is actually kind of a bore. With his passion for being a hero lost along with his hair, yet still faced with new enemies every day, how much longer can he keep it going?

A species of parasitic aliens descends on Earth and quickly infiltrates humanity by entering the brains of vulnerable targets; insatiable beings that gain total control of their host and are capable of transforming themselves to feed on unsuspecting prey. High school student Shinichi Izumi falls victim to one of these parasites, but the creature fails to take over his brain and ends up in his right hand.

Although there are still traces of the brief period he became a vampire, third-year high school student Koyomi Araragi is human again. He happens upon others with their own supernatural problems and finds that he can empathize. Koyomi becomes involved in their lives, seeking to help them and occasionally asking for advice from Meme Oshino, the homeless man who helped him become human again.

Trigun takes place in the distant future on a deserted planet. Vash the Stampede is a gunfighter with a legend so ruthless he has a $$60,000,000,000 bounty on his head. Entire towns evacuate at the rumor of his arrival. But the real Vash the Stampede, the enigmatic and conflicted lead character in Trigun, is more heroic, even though he usually acts like a complete idiot.

Onizuka is an ex-biker and gang leader who has one goal, to become the greatest teacher. He learns of the power and respect possible as an intern teacher, using his strength and connections to get his students to respect him. Now, graduated, he gets a job at a prestigious private school to handle their 'problem class' that made the past few teachers quit. He must handle a different sort of trouble when the trouble makers include some of the smartest kids in Japan who prefer a more cerebral approach to torturing their teacher. Onizuka must slowly win his students over and deal with their mistrust of teachers while handling the distrust of his fellow teachers.

Kintaro Oe is a 25-year-old boy who left Tokyo University and now lives a simple life, traveling by bicycle to learn everything he can about the world.

A group of friends have customized their microwave so that it can send text messages to the past. As they perform different experiments, an organization named SERN who has been doing their own research on time travel tracks them down and now the characters have to find a way to avoid being captured by them.

Edward and Alphonse Elric's reckless disregard for alchemy's fun­damental laws ripped half of Ed's limbs from his body and left Al's soul clinging to a cold suit of armor. To restore what was lost, the brothers scour a war-torn land for the Philosopher's Sto­ne, a fabled relic which grants the ability to perform alchemy in impossible ways.The Elrics are not alone in their search; the corrupt State Military is also eager to harness the artifact's power. So too are the strange Homunculi and their shadowy creator. The mythical gem lures exotic alchemists from distant kingdoms, scarring some deeply enough to inspire murder. As the Elrics find their course altered by these enemies and allies, their purpose remains unchanged – and their bond unbreakable.

In a war-torn world of elemental magic, a young boy reawakens to undertake a dangerous mystic quest to fulfill his destiny as the Avatar, and bring peace to the world.