When a young boy vanishes, a small town uncovers a mystery involving secret experiments, terrifying supernatural forces, and one strange little girl.

The sitcom is centered on five characters living in Pasadena, California: roommates Leonard Hofstadter and Sheldon Cooper; Penny, a waitress and aspiring actress who lives across the hall; and Leonard and Sheldon's equally geeky and socially awkward friends and co-workers, mechanical engineer Howard Wolowitz and astrophysicist Raj Koothrappali. The geekiness and intellect of the four guys is contrasted for comic effect with Penny's social skills and common sense.

The unlikely friendship between Merlin, a young man gifted with extraordinary magical powers, and Prince Arthur, heir to the crown of Camelot.

A man struggling with his faith is haunted by the sins of his past but is suddenly thrust into the role of defending humanity from the gathering forces of darkness.

A comedic thriller that follows the bizarre adventures of eccentric “holistic” detective Dirk Gently and his reluctant assistant Todd. An adaptation of Douglas Adams’ wildly successful comic novels.

When Clary Fray's mother has disappeared, Clary joins a band of Shadowhunters; demon killing hunters, and gets caught up in a plan to save the world.

As her 16th birthday nears, Sabrina must choose between the witch world of her family and the human world of her friends. Based on the Archie comic.

Dr. Megan Hunt was in a class of her own, a brilliant neurosurgeon at the top of her game. But her world is turned upside down when a devastating car accident puts an end to her time in the operating room. Megan resumes her career as a medical examiner, determined to solve the puzzle of who or what killed the victims.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

The Doctor is a Time Lord: a 900 year old alien with 2 hearts, part of a gifted civilization who mastered time travel. The Doctor saves planets for a living—more of a hobby actually, and the Doctor's very, very good at it.

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

The world's leading deception researcher, Dr. Cal Lightman, studies facial expression, body language and tone of voice to determine when a person is lying and why, which helps law enforcement and government agencies uncover the truth. But his skills also make it easier for him to deceive others.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

When they were boys, Sam and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it. Now, the Winchester brothers crisscross the country in their '67 Chevy Impala, battling every kind of supernatural threat they encounter along the way.

A dysfunctional family of superheroes comes together to solve the mystery of their father's death, the threat of the apocalypse and more.