Having left behind Seattle Grace Hospital, renowned surgeon Addison Forbes Montgomery moves to Los Angeles for sunnier weather and happier possibilities. She reunites with her friends from medical school, joining them at their chic, co-op, Oceanside Wellness Center in Santa Monica.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

Patrick Jane, a former celebrity psychic medium, uses his razor sharp skills of observation and expertise at "reading" people to solve serious crimes with the California Bureau of Investigation.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

Xena is an infamous warrior on a quest to seek redemption for her past sins against the innocent. Accompanied her comrade-in-arms Gabrielle, the campy couple use their formidable fighting skills to help those who are unable to defend themselves.

Three sisters (Prue, Piper and Phoebe) reunite and unlock their powers to become the Charmed Ones, the most powerful good witches of all time, whose prophesied destiny is to protect innocent lives from evil beings such as demons and warlocks. Each sister possesses unique magical powers that grow and evolve, while they attempt to maintain normal lives in modern day San Francisco.

From murder and espionage to terrorism and stolen submarines, a team of special agents investigates any crime that has a shred of evidence connected to Navy and Marine Corps personnel, regardless of rank or position.