Bordeaux (Gascon Bordèu ) is a port city on the Garonne in the Gironde department in Southwestern France. The municipality (commune) of Bordeaux proper has a population of 252,040 (2016). Together with its suburbs and satellite towns, Bordeaux is the centre of the Bordeaux Métropole. With 1,195,335 in the metropolitan area, it is the sixth-largest in France, after Paris, Marseille, Lyon, Toulouse, and Lille. It is the capital of the Nouvelle-Aquitaine region, as well as the prefecture of the Gironde department. Its inhabitants are called "Bordelais" (for men) or "Bordelaises" (women). The term "Bordelais" may also refer to the city and its surrounding region. Being at the center of a major wine-growing and wine-producing region, Bordeaux remains a prominent powerhouse and exercises significant influence on the world wine industry although no wine production is conducted within the city limits. It is home to the world's main wine fair, Vinexpo, and the wine economy in the metro area takes in 14.5 billion euros each year. Bordeaux wine has been produced in the region since the 8th century. The historic part of the city is on the UNESCO World Heritage List as "an outstanding urban and architectural ensemble" of the 18th century. After Paris, Bordeaux has the highest number of preserved historical buildings of any city in France.