Colmar (Colmar, Alsatian: Colmer German during 1871–1918 and 1940–1945: Kolmar) is a city and commune in the Haut-Rhin department and Grand Est region of north-eastern France. The third-largest commune in Alsace (after Strasbourg and Mulhouse), it is the seat of the prefecture of the Haut-Rhin department and of the subprefecture of the Colmar-Ribeauvillé arrondissement. The city is renowned for its well-preserved old town, its numerous architectural landmarks, and its museums, among which is the Unterlinden Museum, which houses the Isenheim Altarpiece. Colmar is situated on the Alsatian Wine Route and considers itself to be the "capital of Alsatian wine" (capitale des vins d'Alsace).