Ray Ferrier is a divorced dockworker and less-than-perfect father. Soon after his ex-wife and her new husband drop off his teenage son and young daughter for a rare weekend visit, a strange and powerful lightning storm touches down.

In the late 21st century, a subculture of humans have emerged who have been modified genetically by a vampire-like disease, giving them enhanced speed, incredible stamina and acute intelligence. As they are set apart from "normal" and "healthy" humans, the world is pushed to the brink of worldwide civil war aimed at the destruction of the "diseased" population. In the middle of this crossed-fire is - an infected woman - Ultraviolet, who finds herself protecting a nine-year-old boy who has been marked for death by the human government as he is believed to be a threat to humans.

Geophysicist Dr. Josh Keyes discovers that an unknown force has caused the earth's inner core to stop rotating. With the planet's magnetic field rapidly deteriorating, our atmosphere literally starts to come apart at the seams with catastrophic consequences. To resolve the crisis, Keyes, along with a team of the world's most gifted scientists, travel into the earth's core. Their mission: detonate a device that will reactivate the core.