In Tokyo's downtown district of Ikebukuro, amidst many strange rumors and warnings of anonymous gangs and dangerous occupants, one urban legend stands out above the rest—the existence of a headless "Black Rider" who is said to be seen driving a jet-black motorcycle through the city streets.Mikado Ryuugamine has always longed for the excitement of the city life, and an invitation from a childhood friend convinces him to move to Tokyo. Witnessing the Black Rider on his first day in the city, his wishes already seem to have been granted. But as supernatural events begin to occur, ordinary citizens like himself, along with Ikebukuro's most colorful inhabitants, are mixed up in the commotion breaking out in their city.

Mugen is a ferocious, animalistic warrior with a fighting style inspired by break-dancing. Jin is a ronin samurai who wanders the countryside alone. They may not be friends, but their paths continually cross. And when ditzy waitress Fuu gets them out of hot water with the local magistrate, they agree to join her search for the "samurai who smells of sunflowers."

The adventures of young Osomatsu Matsuno and his five sextuplet brothers.

Four men are assigned to the prison: Jūgo, a man who attempted to break out of prison and ended up extending his jail time; Uno, a man who likes to gamble with women; Rock, a man who likes to get into fights; and Nico, a man who likes anime.