The Plastics are back in the long awaited follow-up to the smash-hit Mean Girls and now the clique is more fashionable, funny and ferocious than ever! Confident senior Jo (Meaghan Martin) begins the new school year by breaking her own cardinal rule: don't get involved in girl drama. But when she sees timid Abby (Jennifer Stone) preyed upon by Queen Bee Mandi (Maiara Walsh) and her minions, she takes sides in a viciously funny girl-world-war that turns the whole school upside down.

Cady Heron is a hit with The Plastics, the A-list girl clique at her new school, until she makes the mistake of falling for Aaron Samuels, the ex-boyfriend of alpha Plastic Regina George.