In the unreal world of Sacred Heart Hospital, John "J.D." Dorian learns the ways of medicine, friendship and life.

A father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.

The sitcom is centered on five characters living in Pasadena, California: roommates Leonard Hofstadter and Sheldon Cooper; Penny, a waitress and aspiring actress who lives across the hall; and Leonard and Sheldon's equally geeky and...

The misadventures of a group of friends as they navigate the pitfalls of work, life and love in Manhattan.