В центре сюжета — отношения Антона и Кристины, Маши и Вали, Майкла и Вари, а также непростая история Яны. Ребята выросли и покинули общагу, у них появились семьи, работа, кого-то начал затягивать быт, кого-то настиг возрастной кризис. Жизни героев сложились по-разному, но они по-прежнему дружат и помогают друг другу.

The hostel number 3, in which the heroes lived, is being demolished, and three guys (Michael, Anton and Kuzya) are relocated to a new hostel. In the new building they are settled in block number 510 with the girls Christina, Yana and Masha. Kuzya begins to date Masha, and Anton dates Christina. Later Kuzya leaves for Agapovka, the botanist Valentin is settled instead.

The son of oligarch Sylvestre Sergeev, Sasha, fled from the university in London, where he studied finance, and entered the astronomical department of the physics department of a Moscow university. Sylvester Andreevich wants to return his son to his former life, but he wants to live "among the people" and wants to achieve everything in life himself. In parallel with this, many funny situations happen to the heroes of the series.